Magnesium is an essential mineral involved in over 300 biochemical reactions in your body, from energy production to muscle function and nervous system regulation. Despite its importance, many people don’t get enough magnesium through diet alone, making supplementation a popular choice.
However, not all magnesium supplements are created equal. Different forms of magnesium have varying absorption rates and are better suited for specific health concerns. Understanding these differences can help you choose the right supplement for your individual needs.
Why Magnesium Type Matters
Magnesium supplements combine magnesium with another substance—an amino acid, organic acid, or inorganic compound. This pairing affects how well your body absorbs the magnesium and determines its primary uses and benefits.
Some forms are highly bioavailable (easily absorbed), while others pass through your digestive system with minimal absorption. Additionally, certain forms are specifically beneficial for particular health conditions, from digestive issues to mental health support.
The 10 Main Types of Magnesium Supplements
1. Magnesium Citrate
Magnesium citrate combines magnesium with citric acid, the natural compound that gives citrus fruits their tart flavor. This is one of the most popular and widely available forms of magnesium supplements.
Absorption: Highly bioavailable and easily absorbed by the digestive tract.
Best for:
- Replenishing magnesium deficiency
- Treating constipation due to its natural laxative effect
- General magnesium supplementation
Considerations: The laxative effect can be strong for some individuals, so start with smaller doses if you’re sensitive.
2. Magnesium Glycinate
Magnesium glycinate is formed when magnesium binds with the amino acid glycine. This form is known for being gentle on the stomach and having calming properties.
Absorption: Excellent absorption with minimal digestive side effects.
Best for:
- Sleep support and insomnia
- Anxiety and stress relief
- Depression symptoms
- People with sensitive digestive systems
- Long-term supplementation
Considerations: This is often considered the best all-around form for people who need higher doses without experiencing laxative effects.
3. Magnesium Malate
Magnesium malate contains malic acid, which naturally occurs in fruits like apples and gives them their tart taste. Malic acid plays a role in energy production.
Absorption: Highly bioavailable with good absorption rates.
Best for:
- Energy production and fighting fatigue
- Fibromyalgia symptoms
- Chronic fatigue syndrome
- Muscle pain and soreness
Considerations: Less likely to cause digestive upset compared to magnesium citrate, making it suitable for those who need energy support without laxative effects.
4. Magnesium L-Threonate
Magnesium L-threonate is a newer form created by combining magnesium with threonic acid, a metabolite of vitamin C. This form is unique in its ability to cross the blood-brain barrier.
Absorption: Excellent absorption, particularly in brain tissue.
Best for:
- Cognitive function and brain health
- Memory support and age-related memory decline
- Potential support for depression and anxiety
- Alzheimer’s disease research (though more studies are needed)
Considerations: This form tends to be more expensive than other types but may be worth it for those specifically seeking cognitive benefits.
5. Magnesium Taurate
Magnesium taurate combines magnesium with the amino acid taurine. Both compounds independently support cardiovascular health, making this combination particularly beneficial.
Absorption: Well absorbed with good bioavailability.
Best for:
- High blood pressure management
- Cardiovascular health
- Blood sugar regulation
- Heart rhythm support
Considerations: May be the optimal choice for individuals concerned about heart health, though you should consult with a healthcare provider before using supplements for cardiovascular conditions.
6. Magnesium Oxide
Magnesium oxide is a salt combining magnesium and oxygen. It contains a high percentage of elemental magnesium but has poor bioavailability.
Absorption: Poorly absorbed compared to other forms.
Best for:
- Heartburn and acid reflux relief
- Constipation treatment
- Indigestion
- Migraine prevention (some evidence)
Considerations: Not ideal for treating magnesium deficiency due to poor absorption. However, this property makes it effective for digestive complaints since it remains in the digestive tract.
7. Magnesium Chloride
Magnesium chloride contains chlorine bound to magnesium. It’s available in both oral supplements and topical preparations.
Absorption: Well absorbed when taken orally; topical absorption is less established.
Best for:
- Magnesium deficiency
- Heartburn relief
- Constipation
- Topical use for muscle soreness (though evidence is limited)
Considerations: A versatile multi-purpose supplement that works well for general magnesium supplementation.
8. Magnesium Lactate
Magnesium lactate is the salt formed when magnesium combines with lactic acid. It’s commonly used as a food additive but is also available as a supplement.
Absorption: Easily absorbed and gentle on the digestive system.
Best for:
- People who need high doses of magnesium
- Those with sensitive digestive systems
- Stress and anxiety management (emerging research)
Considerations: An excellent option for those who don’t tolerate other forms well or require large doses regularly.
9. Magnesium Orotate
Magnesium orotate contains orotic acid, a compound involved in the construction of genetic material in your cells. It’s particularly concentrated in heart tissue.
Absorption: Well absorbed without strong laxative effects.
Best for:
- Heart health and cardiovascular support
- Athletic performance and recovery
- Energy production in heart tissue
- Congestive heart failure support (consult your doctor)
Considerations: More expensive than other forms, but early research suggests significant benefits for heart health.
10. Magnesium Sulfate (Epsom Salt)
Magnesium sulfate, commonly known as Epsom salt, combines magnesium with sulfur and oxygen. While it can be taken orally, it’s most commonly used externally.
Absorption: Can be absorbed orally but has strong laxative effects; skin absorption is minimal and not well-established.
Best for:
- Constipation relief (oral use)
- Soaking baths for muscle soreness
- Topical relaxation (though absorption through skin is questionable)
Considerations: Use caution with oral consumption as excessive amounts can be dangerous. For topical use, while popular, scientific evidence for effectiveness is limited.
Magnesium Comparison: Which Type Should You Choose?
For Sleep and Anxiety
Best choice: Magnesium glycinate or magnesium taurate
These forms have calming properties and are less likely to cause digestive upset, making them ideal for evening use.
For Constipation
Best choice: Magnesium citrate or magnesium oxide
Both forms have natural laxative effects. Magnesium citrate is better absorbed for overall health benefits, while magnesium oxide works primarily in the digestive tract.
For High Blood Pressure
Best choice: Magnesium taurate or magnesium orotate
These forms specifically support cardiovascular health, though you should always consult with a healthcare provider before treating blood pressure with supplements.
For Energy and Fatigue
Best choice: Magnesium malate
Malic acid supports energy production, making this form particularly effective for fighting fatigue and supporting muscle function.
For Brain Health and Memory
Best choice: Magnesium L-threonate
This is the only form shown to effectively cross the blood-brain barrier and increase magnesium levels in the brain.
For General Supplementation
Best choice: Magnesium glycinate or magnesium citrate
Both are highly bioavailable. Choose glycinate if you want to avoid laxative effects, or citrate if you also want digestive support.
Magnesium Oxide vs Citrate vs Glycinate: Direct Comparison
These three forms are among the most common, and understanding their differences can help you make an informed choice:
Magnesium Oxide:
- Lowest bioavailability (4%)
- High elemental magnesium content
- Strong laxative effect
- Best for: Digestive issues, not deficiency
- Most affordable option
Magnesium Citrate:
- High bioavailability (approximately 30%)
- Moderate laxative effect
- Best for: General supplementation and mild constipation
- Good balance of effectiveness and cost
Magnesium Glycinate:
- Highest bioavailability (approximately 80%)
- Minimal laxative effect
- Best for: Sleep, anxiety, long-term supplementation
- More expensive but gentler on the stomach
How to Determine Your Magnesium Needs
Signs of Magnesium Deficiency
Common symptoms that may indicate low magnesium levels include:
- Muscle cramps or twitches
- Fatigue and weakness
- Irregular heartbeat
- Numbness or tingling
- Mood changes, anxiety, or depression
- Difficulty sleeping
- Headaches or migraines
Who’s at Risk for Deficiency?
Certain groups are more likely to have low magnesium levels:
- Older adults
- People with type 2 diabetes
- Those with digestive disorders (Crohn’s disease, celiac disease)
- Individuals with alcohol dependence
- People taking certain medications (proton pump inhibitors, diuretics)
Recommended Dosage and Safety Considerations
Daily Magnesium Requirements
The recommended dietary allowance (RDA) for magnesium varies by age and gender:
- Adult men: 400-420 mg daily
- Adult women: 310-320 mg daily
- Pregnant women: 350-360 mg daily
- Older adults may need slightly more
Starting Your Supplement
When beginning magnesium supplementation:
- Start with a lower dose and gradually increase
- Take with food to minimize digestive discomfort
- Divide larger doses throughout the day for better absorption
- Consider taking magnesium glycinate in the evening for sleep support
Potential Side Effects
While magnesium supplements are generally safe, some people may experience:
- Diarrhea (especially with citrate and oxide forms)
- Nausea or upset stomach
- Abdominal cramping
These effects are usually mild and can be minimized by adjusting your dose or switching to a different form like magnesium glycinate.
When to Seek Medical Advice
Consult with a healthcare professional before taking magnesium supplements if you:
- Have kidney disease or impaired kidney function
- Take medications (magnesium can interact with antibiotics, blood pressure medications, and others)
- Have heart rhythm disorders
- Are pregnant or breastfeeding
- Experience symptoms of magnesium toxicity (extremely rare from supplements)
Food Sources of Magnesium
Before turning to supplements, consider increasing magnesium-rich foods in your diet:
Vegetables:
- Spinach and Swiss chard
- Kale and collard greens
- Avocado
- Broccoli
Nuts and Seeds:
- Pumpkin seeds (highest source)
- Almonds
- Cashews
- Brazil nuts
Legumes:
- Black beans
- Chickpeas
- Edamame
- Lentils
Whole Grains:
- Brown rice
- Quinoa
- Oatmeal
- Whole wheat bread
Other Sources:
- Dark chocolate (70% cocoa or higher)
- Fatty fish (salmon, mackerel)
- Bananas
- Tofu
Combining Different Forms of Magnesium
Some people choose to take multiple forms of magnesium to target different health concerns. For example:
- Magnesium glycinate in the evening for sleep
- Magnesium malate in the morning for energy
- Magnesium citrate as needed for digestive support
However, be mindful of your total daily intake to avoid exceeding recommended amounts. The upper limit for supplemental magnesium is 350 mg daily for adults (not counting magnesium from food).
Frequently Asked Questions About Magnesium Types
Which Magnesium Makes You Poop?
Magnesium citrate and magnesium oxide have the strongest laxative effects. Magnesium citrate is often preferred because it’s better absorbed and provides additional health benefits beyond treating constipation.
What’s the Difference Between Magnesium and Magnesium Glycinate?
“Magnesium” is the general term for the mineral, while “magnesium glycinate” is a specific supplement form. All magnesium supplements contain the same mineral but bound to different compounds that affect absorption and benefits.
Can You Take Too Much Magnesium?
Yes, though it’s rare from supplements alone. Magnesium toxicity is more common in people with kidney problems. Your body typically excretes excess magnesium through urine, but very high doses can cause serious side effects.
How Long Does It Take for Magnesium to Work?
This depends on what you’re using it for. Laxative effects may occur within hours, while improvements in sleep or anxiety might take several weeks of consistent supplementation.
The Bottom Line
Understanding the different types of magnesium supplements empowers you to choose the form that best matches your specific health goals. While magnesium glycinate offers excellent overall absorption with minimal side effects, other forms like magnesium citrate, taurate, L-threonate, and malate have unique benefits for specific conditions.
Remember that supplements should complement, not replace, a balanced diet rich in magnesium-containing foods. If you’re experiencing symptoms of deficiency or have specific health concerns, consult with a healthcare professional to determine the appropriate type and dosage for your individual needs.
By selecting the right form of magnesium and using it consistently, you can support your body’s many magnesium-dependent functions and potentially improve various aspects of your health, from sleep quality to cardiovascular function and beyond.
Sources:
- National Institutes of Health – PubMed Central: Magnesium in Health and Disease
- National Institutes of Health Office of Dietary Supplements: Magnesium Fact Sheet
- PubMed Central: Magnesium and Depression
- PubMed Central: Taurine and Magnesium in Metabolic Health
- PubMed Central: Magnesium L-Threonate and Brain Health
- National Library of Medicine: Magnesium Supplementation
⚕️ Medical Disclaimer
This content is for informational purposes only and does not constitute medical advice. The information provided has not been evaluated by the Food and Drug Administration (FDA) and is not intended to diagnose, treat, cure, or prevent any disease.
Always consult with a qualified healthcare professional before making any changes to your diet, taking supplements, or starting any health regimen. Individual results may vary.

