Calibrate Weight Loss Program: Complete Expert Review & Guide

Calibrate has emerged as a unique weight loss solution that combines metabolic science, prescription medication, and personalized coaching. Unlike traditional diet programs, this year-long approach focuses on resetting your metabolism through sustainable lifestyle changes.

If you’re considering Calibrate for your weight loss journey, you’ll want to understand exactly what the program entails, how much it costs, and whether it can deliver on its promises. This comprehensive review examines all aspects of Calibrate to help you make an informed decision.

What Is Calibrate Weight Loss Program?

Calibrate is a telehealth-based weight loss program founded in 2020 that takes a metabolic approach to sustainable weight management. The program distinguishes itself by combining prescription medications with comprehensive lifestyle coaching over a 12-month period.

The core philosophy revolves around what Calibrate calls the “Four Pillars of Metabolic Health”: food, sleep, exercise, and emotional well-being. Rather than focusing solely on calorie restriction, the program aims to optimize your body’s metabolic function for long-term results.

Members receive prescription medications that work by regulating appetite and blood sugar levels, alongside regular video consultations with health coaches who guide them through gradual lifestyle changes. The company claims members lose an average of 15% of their body weight within the first year.

How Does the Calibrate Program Work?

The Calibrate Metabolic Reset program spans 12 months and is structured into four progressive phases, each lasting approximately three months. This gradual approach allows members to build sustainable habits over time.

Phase 1: Learning (Months 1-3)

During the initial three months, you’ll establish the foundation for your weight loss journey. This phase includes biweekly video sessions with your assigned coach, reading 1-2 educational lessons weekly through the app, and beginning your prescribed medication regimen.

The focus is on understanding metabolic health basics and starting to implement small, manageable changes to your daily routine. You’ll learn how different foods, sleep patterns, physical activity, and stress levels affect your metabolism.

Phase 2: Practicing (Months 3-6)

The second quarter builds upon the knowledge gained in Phase 1. You’ll continue meeting with your coach every two weeks while diving deeper into the curriculum with two lessons per week.

This phase emphasizes putting theory into practice as you develop new skills and habits. The program introduces “focus classes” that allow you to concentrate on specific areas where you need extra support or want to deepen your understanding.

Phase 3: Setting (Months 6-9)

By months 6-9, you’ll be working on solidifying the habits you’ve developed. The coaching sessions continue biweekly, and you maintain the rhythm of 1-2 lessons weekly.

During this phase, you gain more autonomy in choosing which pillars to focus on based on your personal goals and challenges. This customization helps ensure the program addresses your specific needs.

Phase 4: Sustaining (Months 9-12)

The final phase prepares you to maintain your results long-term. You’ll continue working with your coach and accessing the curriculum while reinforcing the habits that have proven most effective for you.

This phase emphasizes self-sufficiency while still providing support, helping you transition from active weight loss to sustainable weight maintenance.

Understanding the Medication Component

A distinctive feature of Calibrate is its use of prescription medications as part of the weight loss protocol. The program utilizes medications that were originally developed for diabetes management but have been found to assist with weight loss.

These medications work by influencing hormones that regulate appetite and blood sugar levels, helping reduce hunger and food cravings. When combined with lifestyle changes, they can support significant weight loss in eligible individuals.

Important note: All medications are prescribed by licensed physicians after a thorough medical review. You should never start any weight loss medication without proper medical supervision. Always consult with your healthcare provider to discuss potential benefits, risks, and whether medication-assisted weight loss is appropriate for your situation.

The medications used in the program require self-administered injections on either a daily or weekly basis, depending on which medication is prescribed. While the company states these injections are relatively quick and easy, this may not be comfortable for everyone.

Who Qualifies for Calibrate?

Calibrate has specific eligibility requirements that potential members must meet. Understanding these criteria upfront can help you determine whether the program is accessible to you.

Basic Requirements

• Must be a U.S. resident
• Age between 18-64 years
• Have commercial or employer-sponsored health insurance
• Body Mass Index (BMI) above 30, or BMI above 27 with at least one weight-related health condition

Qualifying Health Conditions

If your BMI is between 27-30, you must have at least one of the following conditions:

• Type 2 diabetes or prediabetes
• High blood pressure
• High cholesterol levels
• Heart disease
• Nonalcoholic fatty liver disease
• Obstructive sleep apnea
• Polycystic ovary syndrome (PCOS)

Who Should Not Use Calibrate

The program is not recommended for individuals who:

• Are pregnant, nursing, or planning pregnancy within 12 months
• Have type 1 diabetes
• Have active eating disorders
• Have certain thyroid conditions or family history of medullary thyroid cancer
• Have active gallbladder disease
• Are currently undergoing cancer treatment
• Have had bariatric surgery within the past 18 months
• Have recent history of pancreatitis
• Have substance use disorders

Calibrate Cost and Pricing Structure

Understanding the full cost of Calibrate is essential before committing to the program. The pricing structure has several components to consider.

Program Membership Fee

The base program cost starts at $138 per month for 12 months, or $1,649 if paid upfront. This fee covers:

• Biweekly one-on-one video coaching sessions
• Complete access to the educational curriculum
• Initial virtual doctor consultation and medical review
• Smart scale and welcome kit
• Ongoing support from medical and customer service teams
• Mobile app with tracking tools and resources

Additional Medication Costs

The prescription medication cost is separate from the program fee. With most commercial insurance plans, the medication typically costs around $25 per month after meeting any applicable deductibles.

However, medication costs can vary significantly depending on your specific insurance coverage. Some members may face higher out-of-pocket expenses. Calibrate provides support in navigating insurance coverage and exploring patient assistance programs.

Payment Options

Members can choose between monthly installments or paying the full annual fee upfront. Some people may be able to use Health Savings Account (HSA) or Flexible Spending Account (FSA) funds to cover the program cost if paying in full.

What Can You Eat on Calibrate?

One of Calibrate’s appealing features is its flexible approach to nutrition. Unlike restrictive diet programs, Calibrate doesn’t eliminate entire food groups or require you to follow a specific meal plan.

The Calibrate Eating Approach

The program guides you toward foods that support metabolic health while allowing you to make choices that fit your preferences and lifestyle. The emphasis is on:

• Reducing fast-digesting carbohydrates: This includes refined grains, white bread, sugary snacks, and sweetened beverages
• Increasing protein intake: Lean meats, fish, eggs, legumes, and plant-based proteins
• Prioritizing fiber-rich foods: Vegetables, fruits, whole grains, beans, and lentils
• Incorporating healthy fats: Nuts, seeds, avocados, olive oil, and fatty fish

Foods to Emphasize

• Non-starchy vegetables (leafy greens, broccoli, peppers, cauliflower)
• Whole fruits (berries, apples, citrus fruits)
• Whole grains (quinoa, brown rice, oats, farro)
• Lean proteins (chicken, turkey, fish, tofu, tempeh)
• Legumes (chickpeas, black beans, lentils)
• Nuts and seeds (almonds, walnuts, chia seeds, flaxseed)
• Healthy fats (avocado, olive oil, fatty fish)

Dietary Flexibility

Calibrate works with various dietary patterns including vegan, vegetarian, kosher, gluten-free, and other restrictions. The program doesn’t require calorie counting or macro tracking, which many people find less burdensome than traditional diets.

This flexible approach aims to help you develop a sustainable way of eating rather than following rigid rules that are difficult to maintain long-term.

Does Calibrate Work for Weight Loss?

The effectiveness of any weight loss program is a critical consideration. Let’s examine the available evidence on Calibrate’s results.

Company-Reported Results

According to Calibrate’s published results reports, members experience significant weight loss:

• Average of 11% body weight loss at 6 months
• Average of 15% body weight loss at 12 months
• Average of 16.5% body weight loss at 18 months for those continuing into a second year
• Average reduction of 6.4 inches from waistline after 12 months

The company also reports improvements in metabolic health markers including blood sugar levels, cholesterol, and triglycerides. Approximately 81% of members complete the first year, with 70% enrolling for a second year.

Supporting Evidence for Program Components

While independent research specifically on Calibrate is limited, scientific evidence supports many components of the program:

Prescription Medications: The class of medications used by Calibrate has been shown in multiple clinical trials to support weight loss when combined with lifestyle changes. These medications work by reducing appetite and helping people feel fuller with less food.

High-Protein, High-Fiber Diet: Research consistently shows that diets rich in protein and fiber help with satiety, reduce overall calorie intake, and support weight loss maintenance.

Regular Physical Activity: Exercise is a well-established component of successful weight management, helping to burn calories and preserve muscle mass during weight loss.

Sleep Optimization: Studies have demonstrated that adequate, quality sleep supports weight loss efforts and helps maintain metabolic health.

Behavioral Coaching: Regular support from coaches can increase accountability and help people maintain lifestyle changes over time.

Important Considerations

The primary research on Calibrate’s effectiveness comes from the company itself rather than independent peer-reviewed studies. While the results appear promising, more independent research would strengthen confidence in the program’s effectiveness.

Additionally, questions remain about long-term weight maintenance after discontinuing the medication, which is an important consideration for anyone contemplating the program.

Benefits of the Calibrate Program

Beyond weight loss, Calibrate offers several advantages that may appeal to different individuals.

Personalized Support and Accountability

Regular coaching sessions provide ongoing support, motivation, and accountability. Having someone to check in with every two weeks can help you stay on track and work through challenges as they arise.

Coaches provide personalized feedback based on your specific situation, helping you set realistic goals and adjust your approach as needed.

Comprehensive Approach to Health

By addressing multiple aspects of metabolic health—food, sleep, exercise, and emotional well-being—Calibrate takes a holistic approach rather than focusing solely on diet or exercise.

This comprehensive strategy may lead to improvements in overall health beyond just the number on the scale, including better sleep quality, increased energy, and improved markers of cardiovascular health.

No Extreme Restrictions

The absence of strict food rules or elimination of entire food groups makes Calibrate more sustainable for many people compared to highly restrictive diets.

You can still enjoy foods you love while learning to make choices that support your metabolic health. This flexibility may reduce feelings of deprivation and make the program easier to stick with long-term.

Gradual, Sustainable Changes

The program’s phased approach introduces changes progressively rather than requiring an overnight overhaul of your lifestyle. This gradual method may feel more manageable and lead to better habit formation.

Skills and behaviors are reinforced throughout the year, increasing the likelihood that changes will stick even after the program ends.

Medical Supervision

Having medical oversight ensures that your weight loss is supervised by healthcare professionals who can monitor for potential issues and adjust your treatment as needed.

Potential Drawbacks and Limitations

While Calibrate offers benefits, it’s important to consider potential downsides before enrolling.

High Cost

At $138 per month plus medication costs, Calibrate is significantly more expensive than many other weight loss programs. The total first-year cost can easily exceed $2,000-$3,000 depending on medication coverage.

This price point may be prohibitive for many people, especially since insurance typically doesn’t cover the program fee itself.

Requires Long-Term Commitment

The 12-month program requires dedication and consistency. While you can cancel at any time, you’ll only receive a full refund if you cancel before your first doctor visit.

This extended commitment may feel daunting if you’re unsure about whether the program is right for you or if your circumstances might change during the year.

Injectable Medication Requirement

The need to self-administer injections (daily or weekly depending on the medication) may be uncomfortable or unacceptable for some individuals. While the company states the injections are quick and relatively painless, needle anxiety is real for many people.

Strict Eligibility Criteria

Many people interested in the program won’t qualify due to the strict requirements around BMI, age, location, insurance, and medical history. This limits who can access the program.

Limited Independent Research

The lack of independent, peer-reviewed research specifically on the Calibrate program means we must rely primarily on company-reported data. While these results appear positive, independent verification would be valuable.

Questions About Long-Term Maintenance

Research on similar medications suggests that some weight regain is common after discontinuing treatment. One study found that participants regained approximately two-thirds of their lost weight within a year of stopping medication.

While the lifestyle changes learned through Calibrate may help mitigate this, it’s unclear how well members maintain their weight loss after completing the program without continued medication use.

Coaches Are Not Healthcare Professionals

While Calibrate coaches provide valuable support and guidance, they are not registered dietitians, psychologists, or other licensed healthcare professionals. For some people, working with credentialed professionals may be preferable.

Possible Side Effects and Safety Concerns

As with any weight loss program involving medication, it’s crucial to understand potential side effects and safety considerations.

Common Side Effects

The medications used in the Calibrate program may cause side effects including:

• Nausea and vomiting
• Diarrhea or constipation
• Abdominal pain or bloating
• Headaches
• Fatigue and dizziness
• Indigestion and acid reflux
• Gas and belching
• Low blood sugar (especially in people with diabetes)

Many of these side effects are most common when starting the medication or increasing the dose, and they often improve over time as your body adjusts.

Serious Potential Risks

More serious but less common risks include:

• Pancreatitis (inflammation of the pancreas)
• Gallbladder problems
• Kidney issues
• Thyroid tumors (observed in animal studies)
• Severe allergic reactions

Because of these potential risks, certain individuals should not use these medications, including those with personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome.

Medical Monitoring

Calibrate includes medical oversight throughout the program, with regular check-ins and the ability to contact the medical team if concerns arise. This supervision is important for managing potential side effects and ensuring the program remains safe for you.

Always consult with your healthcare provider before starting any weight loss program involving medication. Your doctor can help determine whether the benefits outweigh the risks in your specific situation.

Customer Reviews and Reputation

Examining customer feedback provides valuable insight into real-world experiences with the program.

Positive Feedback

Many satisfied customers report:

• Significant weight loss results
• Helpful and supportive coaching
• Appreciation for the flexible eating approach
• Improved metabolic health markers
• Sustainable lifestyle changes
• Reduced hunger and cravings

Common Complaints

Negative reviews often mention:

• Difficulty filling prescriptions due to medication shortages
• Poor customer service responsiveness
• Challenges obtaining refunds
• High cost relative to results
• Side effects from medications
• Limited coach availability or expertise

Better Business Bureau Rating

As of recent reports, Calibrate is not accredited by the Better Business Bureau and holds a low rating based on complaint history. However, ratings should be considered in context, as they may not represent the full picture of customer experiences.

The company has addressed some concerns by noting that prescription filling issues are often due to industry-wide medication shortages beyond their control.

Comparing Calibrate to Other Weight Loss Programs

Understanding how Calibrate stacks up against alternatives can help you make the best choice for your needs.

Calibrate vs. Weight Watchers (WW)

Weight Watchers uses a points-based system and costs $23-$45 per month—significantly less than Calibrate. WW doesn’t involve prescription medications and offers in-person meeting options. However, it may not be as effective for people with metabolic issues who could benefit from medical intervention.

Calibrate vs. Noom

Noom focuses on psychology-based behavior change through an app at a lower cost ($60-$70/month). It doesn’t include prescription medications or video coaching sessions. Noom may be better for those seeking a budget-friendly, psychology-focused approach, while Calibrate suits those wanting medical intervention.

Calibrate vs. Found

Found is similar to Calibrate, offering prescription medications and coaching for weight loss at $99-$129 per month. Both programs have similar structures, though specific medications, coaching frequency, and curriculum differ. Comparing eligibility criteria and medication options for both may help you choose.

Calibrate vs. Traditional Medical Weight Loss

Working with your own doctor or a weight loss clinic provides personalized medical care and may be covered by insurance. However, you may not receive the structured curriculum and regular coaching that Calibrate provides. Cost varies widely depending on your healthcare coverage.

Tips for Success on Calibrate

If you decide to join Calibrate, these strategies can help maximize your results:

Engage Fully with Your Coach

Make the most of your biweekly coaching sessions by coming prepared with questions, being honest about challenges, and actively participating in goal-setting. The more you put into coaching, the more you’ll get out.

Complete the Curriculum Consistently

Don’t skip the weekly lessons—they provide valuable information and strategies for long-term success. Even when busy, prioritize this education component.

Track Your Progress

Use the app’s tracking tools to monitor your weight, measurements, and other health markers. This data helps you and your team identify what’s working and what needs adjustment.

Manage Medication Side Effects

If you experience side effects, communicate with your medical team rather than suffering in silence or discontinuing the medication without guidance. Often, adjusting the dose or timing can help.

Focus on All Four Pillars

Don’t neglect sleep, exercise, or emotional health in favor of focusing solely on food. True metabolic health requires attention to all four pillars.

Build Your Support System

Share your goals with family and friends who can support your lifestyle changes. Their encouragement can be invaluable during challenging times.

Plan for Long-Term Maintenance

As you near the end of the program, work with your coach and medical team to develop a maintenance plan. Consider what aspects of the program you’ll continue and how you’ll maintain your results.

Frequently Asked Questions

How much weight can you lose on Calibrate?

According to company data, members lose an average of 15% of their body weight over 12 months. Individual results vary based on starting weight, adherence to the program, and personal factors. Some people lose more, while others lose less.

Does insurance cover Calibrate?

Insurance typically doesn’t cover the Calibrate program fee itself, but it may cover your lab work and prescription medications. Some people can use HSA or FSA funds for the program cost if paying upfront.

Can you do Calibrate without medication?

No, prescription medication is a core component of the Calibrate program. If you’re looking for a non-medication approach, you might consider alternatives like Weight Watchers, Noom, or working with a registered dietitian.

How do I cancel Calibrate?

You can cancel by emailing Calibrate with “Cancellation Request” in the subject line. You’ll receive a full refund only if you cancel before your first doctor visit. After that, refunds are prorated or unavailable depending on when you cancel.

What happens after the year is over?

After completing the 12-month program, you can choose to enroll in a second year to continue receiving support and medication. Alternatively, you can work with your doctor to develop a maintenance plan. Some people continue the medication through their personal physician.

Are Calibrate coaches qualified?

Calibrate coaches receive training in the program’s methodology but are not required to be registered dietitians, psychologists, or other licensed healthcare professionals. Medical oversight is provided separately by licensed physicians.

What if the medication doesn’t work for me?

If you don’t lose at least 10% of your body weight after completing the full program, Calibrate offers a refund. Additionally, if one medication doesn’t work well or causes intolerable side effects, your doctor may be able to prescribe an alternative.

Is Calibrate Right for You?

Deciding whether to invest in Calibrate requires careful consideration of your personal situation, goals, and preferences.

Calibrate May Be a Good Fit If You:

• Meet all eligibility criteria including BMI, age, and insurance requirements
• Have struggled to lose weight through diet and exercise alone
• Are open to taking prescription medication as part of your weight loss plan
• Can afford the program cost and potential medication expenses
• Are comfortable with self-administered injections
• Want structured support and education alongside medication
• Prefer a flexible eating approach without strict food rules
• Can commit to a year-long program
• Are looking for a comprehensive approach addressing multiple aspects of health

Consider Other Options If You:

• Don’t meet the eligibility criteria
• Have concerns about taking prescription medication for weight loss
• Are uncomfortable with self-administered injections
• Cannot afford the $138/month program fee plus medication costs
• Prefer working with licensed healthcare professionals like registered dietitians
• Want to try lifestyle changes alone before considering medication
• Are looking for a shorter-term program
• Need more flexibility than a structured year-long commitment provides

Next Steps

Before enrolling in Calibrate:

1. Consult your healthcare provider: Discuss whether medication-assisted weight loss is appropriate for you and whether Calibrate aligns with your health needs.
2. Review your insurance coverage: Understand what portion of medication costs your insurance will cover and whether you have HSA/FSA funds available.
3. Calculate total costs: Factor in both the program fee and estimated medication expenses to ensure it fits your budget.
4. Take the eligibility quiz: Complete Calibrate’s online assessment to confirm you qualify.
5. Research alternatives: Compare Calibrate with other programs to ensure you’re choosing the best option for your needs.
6. Set realistic expectations: Understand that results vary and that maintaining weight loss may require ongoing effort after the program ends.

The Bottom Line

Calibrate offers a comprehensive, medically-supervised approach to weight loss that combines prescription medication with lifestyle coaching and education. For people who meet the eligibility criteria and can afford the investment, it provides structured support and has shown promising results in company-reported data.

The program’s emphasis on metabolic health, flexible eating approach, and holistic focus on multiple lifestyle factors distinguishes it from many traditional diet programs. The combination of medication and behavioral support may be particularly effective for individuals who have struggled with other weight loss methods.

However, significant considerations include the high cost, need for injectable medications, strict eligibility requirements, and questions about long-term weight maintenance after completing the program. The lack of independent research and mixed customer reviews also warrant careful evaluation.

Ultimately, Calibrate represents one tool in the weight management toolkit—one that may be highly effective for the right person but isn’t suitable for everyone. As with any significant health decision, consultation with trusted healthcare professionals is essential before committing to this or any weight loss program.

Weight loss is a personal journey, and the best program is one that fits your individual needs, preferences, health status, and life circumstances. Take time to thoroughly research your options, consider alternatives, and make an informed decision that supports your long-term health and well-being.

Sources:

• National Center for Biotechnology Information (NCBI)
• U.S. Food and Drug Administration (FDA)
• National Institutes of Health (NIH)
• Centers for Disease Control and Prevention – Obesity
• Mayo Clinic – Weight Loss
• National Institute of Diabetes and Digestive and Kidney Diseases – Weight Management
• Obesity Action Coalition
• Calibrate Official Website