The age-old saying “beer before liquor, never been sicker; liquor before beer, you’re in the clear” has been passed down through generations of drinkers. This rhyming advice suggests that the order in which you consume different types of alcoholic beverages can determine whether you’ll wake up with a pounding headache and nausea the next morning.
But is there any scientific truth behind this popular drinking wisdom, or is it just another myth that persists despite lacking evidence? Understanding what actually causes hangovers and how alcohol affects your body can help you make informed decisions about drinking responsibly.
This comprehensive guide examines the science behind drinking order, explores the real factors that contribute to hangovers, and provides evidence-based strategies for minimizing their effects.
Understanding the Popular Saying
The phrase “beer before liquor, never been sicker; liquor before beer, you’re in the clear” is deeply ingrained in drinking culture across the United States and many other countries. Despite its widespread recognition, the exact origins of this saying remain unclear.
The rhyme suggests a simple rule: if you start your evening with beer and then switch to liquor (spirits like vodka, whiskey, rum, or gin), you’re more likely to experience severe hangover symptoms. Conversely, if you begin with liquor and transition to beer, you’ll supposedly feel better the next day.
Several theories attempt to explain how this saying came to be. One common explanation is that people typically follow a natural drinking progression throughout an evening, starting with lower-alcohol beverages like beer or wine and gradually moving to stronger drinks as the night continues. If they end up feeling sick, they might incorrectly attribute their discomfort to the drinking order rather than the total amount consumed.
The Science of Alcohol Absorption
To understand whether drinking order matters, it’s essential to know how your body processes alcohol. When you consume an alcoholic beverage, absorption begins almost immediately upon reaching your stomach, with most alcohol being absorbed through the small intestine.
Alcohol enters your bloodstream within minutes of consumption, and your blood alcohol concentration (BAC) rises as you continue drinking. The rate of absorption can vary based on several factors, but the type of alcohol itself isn’t as important as you might think.
Your liver metabolizes alcohol at a relatively constant rate, typically processing about one standard drink per hour. This means that regardless of whether you drink beer, wine, or liquor first, all the alcohol consumed throughout the evening will be absorbed and processed by your body in a similar timeframe.
The key point is that by the time a hangover develops—usually several hours after you’ve stopped drinking—all the alcohol from the previous night has already been absorbed into your bloodstream. The order in which different drinks entered your system becomes irrelevant.
Why Drinking Order Doesn’t Actually Matter
Scientific research doesn’t support the idea that drinking beer before liquor makes hangovers worse. A study conducted by researchers examined whether the order of alcoholic beverage consumption affected hangover severity, and the results were clear: drinking order had no significant impact on hangover symptoms.
The main factor that determines hangover severity is the total amount of alcohol consumed, not the sequence in which different types of drinks are consumed. Whether you have three beers followed by three shots of whiskey, or three shots of whiskey followed by three beers, your body receives the same total amount of alcohol.
However, there’s an important caveat: certain drinking patterns might indirectly lead you to consume more alcohol overall. For example, if switching from beer to liquor causes you to drink more quickly or lose track of how much you’ve consumed, you might end up with a higher total alcohol intake, which would indeed increase hangover risk.
Similarly, the carbonation in beer and sparkling wines can cause alcohol to be absorbed slightly more quickly, but this effect is minimal and doesn’t significantly impact overall hangover severity compared to the total volume consumed.
What Actually Causes Hangovers
Hangovers are complex physiological responses involving multiple body systems. Understanding the actual mechanisms behind hangovers can help you better prevent them, regardless of what you drink or in what order.
Dehydration and Electrolyte Imbalance
Alcohol is a diuretic, meaning it increases urine production and can lead to dehydration. When you’re dehydrated, you may experience headaches, dizziness, and fatigue—common hangover symptoms. Alcohol also affects your body’s electrolyte balance, which can contribute to feeling unwell.
Acetaldehyde Toxicity
When your liver breaks down alcohol, it produces acetaldehyde, a toxic compound that’s more harmful than alcohol itself. Acetaldehyde is eventually metabolized into less harmful substances, but it can accumulate temporarily and contribute to nausea, vomiting, and other hangover symptoms.
Inflammation and Immune Response
Alcohol consumption triggers an inflammatory response in your body and affects your immune system. This inflammation can contribute to various hangover symptoms, including difficulty concentrating, mood changes, and general malaise.
Sleep Disruption
Although alcohol might help you fall asleep initially, it significantly disrupts sleep quality, particularly during the second half of the night. Poor sleep quality contributes to fatigue, irritability, and reduced cognitive function the next day.
Real Factors That Affect Hangover Severity
Instead of worrying about drinking order, focus on these scientifically-supported factors that genuinely influence whether you’ll experience a hangover and how severe it will be.
Total Amount of Alcohol Consumed
This is the single most important factor. The more you drink, the higher your blood alcohol concentration rises, and the more likely you are to experience a hangover. Limiting your total alcohol intake is the most effective way to prevent hangovers.
Drinking on an Empty Stomach
When you drink without eating, alcohol moves more quickly from your stomach to your small intestine, where it’s absorbed rapidly into your bloodstream. This causes faster and higher spikes in blood alcohol levels. Eating before and while drinking helps slow alcohol absorption and can reduce hangover severity.
Drinking Frequency and Tolerance
Regular heavy drinkers may develop some tolerance to alcohol’s immediate effects, but research suggests that repeated heavy drinking doesn’t necessarily protect against hangovers. In fact, frequent heavy drinking may actually increase hangover severity over time.
Hydration Status
Starting your evening well-hydrated and drinking water throughout the night can help counteract alcohol’s diuretic effects. Alternating alcoholic drinks with water is a practical strategy for staying hydrated and naturally slowing your pace of alcohol consumption.
Congeners in Different Alcoholic Beverages
Congeners are chemical compounds produced during fermentation and aging that contribute to the color, taste, and aroma of alcoholic beverages. Darker liquors like bourbon, whiskey, and red wine generally contain higher levels of congeners than clear spirits like vodka or white wine.
Some research suggests that beverages high in congeners may produce worse hangovers than those with lower congener content, though the total amount of alcohol consumed remains the most significant factor.
Genetic Factors
Your genetics play a significant role in how your body metabolizes alcohol and how susceptible you are to hangovers. Genetic variations affect enzymes involved in alcohol metabolism, which influences how quickly alcohol and its toxic byproducts are processed.
Some people have genetic variations that make them more prone to experiencing negative effects from alcohol, while others may rarely experience hangovers regardless of how much they drink. This genetic variability helps explain why hangover experiences differ so dramatically between individuals.
Smoking and Other Substances
Research indicates that people who smoke while drinking are more likely to experience hangovers compared to non-smokers who consume the same amount of alcohol. The combination of alcohol and nicotine may enhance the toxic effects and contribute to worse symptoms the next day.
Age and Overall Health
As people age, their bodies often become less efficient at metabolizing alcohol, which can lead to more severe hangovers. Overall health status, including liver function, nutritional status, and other medical conditions, can also influence hangover susceptibility.
Evidence-Based Strategies to Reduce Hangover Risk
While there’s no guaranteed way to completely prevent hangovers if you choose to drink, these science-backed strategies can help minimize your risk and reduce symptom severity.
Set Limits and Pace Yourself
Decide in advance how many drinks you’ll have and stick to that limit. Space your drinks out over time, aiming for no more than one standard drink per hour. This gives your body time to metabolize the alcohol and helps prevent your blood alcohol concentration from spiking too high.
Eat Before and During Drinking
Never drink on an empty stomach. Eating a substantial meal before you start drinking and snacking throughout the evening slows alcohol absorption and helps maintain steadier blood alcohol levels. Foods containing proteins, fats, and complex carbohydrates are particularly effective.
Stay Hydrated
Drink a glass of water between alcoholic beverages, and have a large glass of water before bed. Starting your evening well-hydrated by drinking plenty of water earlier in the day can also help. Proper hydration won’t completely prevent a hangover if you drink excessively, but it can reduce symptom severity.
Choose Your Beverages Wisely
If you’re sensitive to congeners, opt for clear spirits like vodka or gin rather than darker liquors. However, remember that the total amount of alcohol matters most—drinking large quantities of any type of alcohol can still result in a hangover.
Avoid Smoking
If you smoke, try to avoid or minimize smoking while drinking, as the combination appears to increase hangover risk and severity.
Get Adequate Sleep
While alcohol disrupts sleep quality, allowing enough time for sleep can help your body recover. Avoid staying out extremely late if you’ve been drinking heavily, and create a comfortable sleep environment to maximize rest quality.
Know Your Limits
Understanding how alcohol affects you personally is crucial. Pay attention to how different amounts and types of alcohol impact you, and adjust your drinking habits accordingly. If you consistently experience severe hangovers, consider reducing your alcohol intake.
When to Seek Medical Advice
While occasional hangovers after social drinking are common and generally not dangerous, certain situations warrant medical attention. Consult a healthcare provider if you experience:
- Frequent hangovers that interfere with daily activities or responsibilities
- Difficulty controlling your drinking or feeling unable to limit consumption
- Severe symptoms such as persistent vomiting, confusion, seizures, or irregular breathing
- Signs of alcohol poisoning, including unconsciousness or inability to wake up
- Concerns about alcohol dependence or addiction
A healthcare professional can provide personalized guidance and support if you’re experiencing problematic drinking patterns or severe reactions to alcohol.
The Bottom Line on Drinking Order
The popular saying “beer before liquor, never been sicker” is not supported by scientific evidence. The order in which you consume different types of alcoholic beverages has minimal impact on whether you’ll experience a hangover or how severe it will be.
What truly matters is the total amount of alcohol you consume, how quickly you drink, whether you eat before and during drinking, your hydration status, and individual factors like genetics and overall health. By the time hangover symptoms develop, all the alcohol from the previous evening has already been absorbed and metabolized, making the sequence of consumption irrelevant.
Rather than relying on drinking myths and rhymes, focus on evidence-based strategies for responsible drinking: set limits, pace yourself, eat food, stay hydrated, and know your personal limits. These approaches are far more effective at preventing hangovers than worrying about whether you should have beer or liquor first.
Remember that the most reliable way to avoid a hangover is to drink in moderation or abstain from alcohol entirely. If you choose to drink, understanding the real factors that contribute to hangovers empowers you to make informed decisions that can help you feel better the next day.
Sources:
- National Institutes of Health – Alcohol Metabolism and Absorption
- PubMed Central – Hangover Characteristics and Risk Factors
- NIH National Library of Medicine – Alcohol Hangover Research
- National Institute on Alcohol Abuse and Alcoholism
- Centers for Disease Control and Prevention – Alcohol Facts
- NIAAA – Understanding Hangovers
⚕️ Medical Disclaimer
This content is for informational purposes only and does not constitute medical advice. The information provided has not been evaluated by the Food and Drug Administration (FDA) and is not intended to diagnose, treat, cure, or prevent any disease.
Always consult with a qualified healthcare professional before making any changes to your diet, taking supplements, or starting any health regimen. Individual results may vary.

